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This is thought to be due to its ability to activate multiple receptors, including the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide receptor, which work together to regulate blood sugar levels and insulin secretion

PubMed Jastreboff, A.M., Aronne, L.J., Ahmad, N.N., Wharton, S., Connery, L., Alves, B., Kiyosue, A., Zhang, S., Liu, B., Bunck, M.C., Stefanski, A., & SURMOUNT-1 Investigators

Dietary changes Drink fluids Drinking plenty of water throughout the day helps soften stools and support regular bowel movements

Progress photos capture visual changes the scale misses

The longer duration may have allowed compensatory mechanisms to develop